Description
This medicine inhibits to the binding of aldosterone to receptors which is involved in hypertensive effects, heart and vascular fibrosis, heart hypertrophy or ventricular arrhythmia. It consequently shows antihypertensive effects and anti-heart failure effects.
It is usually used to treat hypertension and chronic heart failure (for the case of receiving base treatment such as ACE inhibitors, angiotensin II receptor antagonist, beta-blocker or diuretic).
Presentation
Feature
Active Ingredients
Eplerenone
Effect/Efficacy
This medicine inhibits to the binding of aldosterone to receptors which is involved in hypertensive effects, heart and vascular fibrosis, heart hypertrophy or ventricular arrhythmia. It consequently shows antihypertensive effects and anti-heart failure effects.
It is usually used to treat hypertension and chronic heart failure (for the case of receiving base treatment such as ACE inhibitors, angiotensin II receptor antagonist, beta-blocker or diuretic).
Usage/Dosage
For treatment of hypertension: In general, for adults, start with 2 tablets (50 mg of the active ingredient) at a time, once a day. If it is not effective enough, the dosage may be increased up to 4 tablets (100 mg) per day. However, if you take the medicine in combination with other medicinal products that suppress its metabolism, the daily dosage may not be exceeded 1 tablet (25 mg) at a time, once a day.
For treatment of chronic heart failure: In general, for adults, start with 1 tablet (25 mg of the active ingredient) at a time, once a day. After 4 weeks from the start of taking as a guide, the dosage may be increased up to 2 tablets (50 mg) at a time, once a day according to the serum potassium level or conditions. However, if you have moderate renal dysfunction, start with 1 tablet (25 mg) at a time, once a day alternately. The maximum daily dose is up to 1 tablet (25 mg) at a time, once a day, the dosage may be decreased or discontinue according to the serum potassium level or conditions. If you take the medicine in combination with other medicinal products that suppress its metabolism, the daily dosage may not be exceeded 1 tablet (25 mg) at a time, once a day.
In any case, strictly follow the instructions.
If you miss a dose and remember it within one day, take the missed dose as soon as possible. You should never take two doses at one time.
If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
Do not stop taking this medicine unless your doctor instructs you to do so.
Cautions
Precautions while taking this medicine :
Since this medicine may cause dizziness by declining blood pressure, pay close attention to performing dangerous operations machinery such as driving a car or working at heights.
Avoid taking health supplements containing St. John's wort (a kind of herb) with the medicine, since it may diminish medicinal effects with its enhanced metabolism.
Contraindication
The most commonly reported adverse reactions include headache, dizziness, nausea, fatigue, hypotension, renal dysfunction, indigestion and muscle cramp. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
numbness of limbs or lips, muscle weakness, paralysis of limbs [hyperkalemia]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.
