Description
This medicine inhibits
decarboxylase outside the brain, transmits dopamine into the brain efficiently
to supplement insufficient dopamine in the brain, and consequently improves
symptoms associated with Parkinson's disease.
It is usually used in the treatment of Parkinson's disease and parkinsonian
syndrome.
Presentation
100 tablets
Feature
elliptically-shaped,
pale blue tablet (major axis: 12.9 mm, minor axis: 7.2 mm, thickness: 3.0 mm)
Active Ingredients
Levodopa, Carbidopa
Effect/Efficacy
This medicine inhibits
decarboxylase outside the brain, transmits dopamine into the brain efficiently
to supplement insufficient dopamine in the brain, and consequently improves
symptoms associated with Parkinson's disease.
It is usually used in the treatment of Parkinson's disease and parkinsonian
syndrome.
Usage/Dosage
If you have never
taken levodopa before: In general, for adults, the initial dose is started at
100 to 125 mg of levodopa at a time, 100 to 300 mg daily, and the dose is
increased by 100 to 125 mg every day or every other day, then the optimal dose
is determined as the maintenance dose (standard dose is 200 to 250 mg of
levodopa at a time, 3 times daily).
If you have been taking levodopa: In general, for adults, take at least 8-hour
interval after taking levodopa alone, the initial dose is determined based on
equivalent to one fifth of levodopa of the daily maintenance dose, and take it
in 3 divided doses daily.
The dosage may be adjusted according to the symptoms in any case, however, the
daily dose should not be exceeded 1,500 mg of levodopa. This preparation
contains 100 mg of levodopa in a tablet. Strictly follow the instructions.
If you miss a dose, take a dose as soon as possible when you remembered that
you missed a dose. However, if it is almost time for the next dose, skip the
missed dose and continue your regular dosing schedule. You should never take
two doses at one time.
If you accidentally take more than your prescribed dose, consult with your
doctor or pharmacist.
Do not stop taking this medicine unless your doctor instructs you to do so.
Cautions
If you have previously
experienced any allergic reactions (itch, rash, etc.) to any medicines.
If you have: glaucoma, hepatic disorder, renal disorder, diabetes, cardiac
disease, pulmonary disease, bronchial asthma, or psychiatric symptom such as
suicidality.
If you are pregnant or breastfeeding.
If you are taking any other medicinal products. (Some medicines may interact to
enhance or diminish medicinal effects. Beware of over-the-counter medicines and
dietary supplements as well as other prescription medicines.)
Keep the medicine out of the reach of children. Store it away from light, heat
(including in a car).
Discard the remainder. Do not store them.
[Families] Gambling, excessive unplanned shopping, and an abnormal rise in
sexual desire and appetite have been reported. Therefore, if these symptoms
occur, consult your doctor or pharmacist.
Contraindication
The medicine may cause
drowsiness or sudden sleep; decline of attention, concentration or reflection.
Avoid driving a car or operating dangerous machinery after taking the medicine.
Gambling, excessive unplanned shopping, and an abnormal rise in sexual desire
and appetite have been reported. Therefore, if these symptoms occur, consult
your doctor or pharmacist.
The most commonly reported adverse reactions include dyskinesia (continuous
involuntary movements of the tongue or jaw), nausea, loss of appetite,
dizziness and insomnia. If any of these symptoms occur, consult with your
doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse
reactions indicated in brackets. If any of these symptoms occur, stop taking
this medicine and see your doctor immediately.
sudden high fever, muscle rigidity, limb tremor [neuroleptic malignant
syndrome]
seeing something that is not really there, feeling like doing
nothing [hallucination/delusion/mental confusion, depression]
epigastric pain, tenderness in the upper abdomen, nausea [deterioration of
gastric or duodenal ulcer]
anemia symptoms, jaundice, nosebleed/bleeding of gums [hemolytic anemia,
thrombopenia]
sudden drowsiness [sudden sleep]
severe eye pain, headache, nausea [closed-angle glaucoma]
The above symptoms do not describe all the adverse reactions to this medicine.
Consult with your doctor or pharmacist if you notice any symptoms of concern
other than those listed above.
