Description
This medicine acts antagonistically upon the receptor for angiotensin II which is a pressor substance and also acts on the calcilum channel of smooth muscle of blood vessels to reduce resistance of peripheral blood vessels and eventually lower blood pressure.
It is usually used to treat hypertension.
Presentation
Feature
Active Ingredients
Azilsartan
Amlodipine besilate
Effect/Efficacy
This medicine acts antagonistically upon the receptor for angiotensin II which is a pressor substance and also acts on the calcilum channel of smooth muscle of blood vessels to reduce resistance of peripheral blood vessels and eventually lower blood pressure.
It is usually used to treat hypertension.
Usage/Dosage
Cautions
For adults: In general, take 1 tablet at a time, once a day. Strictly follow the instructions.
If you miss a dose, take the missed dose as soon as possible. If there is less than 8 hours to the next dose, skip the missed dose and take the next dose at your regular time. You should never take two doses at one time.
If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
Do not stop taking this medicine unless your doctor instructs you to do so.
Precautions while taking this medicine
As dizziness and light-headedness may appear due to excessive lowering of blood pressure. Therefore, be aware of working at heights or operating dangerous machinery such as driving a car.
Do not take this medicine together with grapefruits juice as it may enhance antihypertensive effect of the medicine.
Possible adverse reactions to this medicine
The most commonly reported adverse reactions include eczema, dizziness, light-headedness, swelling, bradycardia, palpitation, decreased blood presure, hot flash, headache, diarrhea, pain in the pit of stomach, constipation, stomatitis, and gingival hyperplasia. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
facial/tongue/throat swelling, breathlessness [angioedema]
feeling cold, vomiting, falling unconscious [shock, syncope, loss of consciousness] decreased urination output, swelling of face and hands/feet, fever [acute renal failure] numbness of hands/feet and lips, muscle weakness [hyperkalemia] yellowing of the skin or whites of the eyes, dullness, loss of appetite [liver dysfunction, jaundice] nose bleeding, gingival bleeding, subcutaneous hemorrhage, fever, throat pain [decreased platelet count, decreased white blood cell] bradycardia, dizziness [atrioventricular block]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.
Contraindication
