等待内容更新

【药品名称】

  通用名称：左卡尼汀口服溶液

  商品名称：左卡尼汀口服溶液

  英文名称：Levocarnitine Oral Solution

【主要成份】 左卡尼汀。

【成 份】

  化学名：(R)-左卡尼汀口服溶液3-羧基-2-羟基-N，N，N-三甲基-1-丙胺氢氧化物，内盐

   分子量：C7H15N03

【性 状】 本品为无色的澄明液体;微香,味甜。

【适应症/功能主治】 用于防治左卡尼汀缺乏。如慢性肾衰病人因血液透析所致的左卡尼汀缺乏。

【规格型号】 10%:5ml*10包

【用法用量】 口服,用餐时服用.成人每日1-3g(1-3支),分2-3次服用;儿童起始剂量每公斤体重50mg,根据需要和耐受性缓慢加大剂量,通常剂量为每公斤体重50-100mg(最大剂量一天不超过3g)。

【不良反应】 偶有口干、胃肠道轻度不适,停药后可自行消失。

【禁 忌】 对本品过敏者禁用。

【注意事项】 用胰岛素或口服降糖药物治疗的糖尿病患者,由于改善葡萄糖的利用,在服用本品时,可能引起低血糖现象,因此,这些患者在接受治疗中血糖应当保持在经常控制的数值以内。 本品含有少量乙醇,对乙醇过敏的病人慎用。
请仔细阅读说明书并遵医嘱使用。

【儿童用药】 尚不明确。

【老年患者用药】 尚不明确。

【孕妇及哺乳期妇女用药】 妊娠期间，只有在明显需要时才使用本剂。尚不清楚这种药是否能进入母乳，应根据该药对母亲的重要性，决定是停止哺乳还是停止用药。

【药物相互作用】 尚不明确。

【药物过量】 尚不明确。

【药理毒理】 左卡尼汀是哺乳动物能量代谢中必需的体内天然物质,其主要功能是促进脂类代谢。它既能将长链脂肪酸带进线粒体基质,并促进其氧化分解,为细胞提供能量,又能将线粒体内产生的短链脂酰基输出。本品的补充可缓解其因体内缺乏引起的脂肪代谢紊乱、骨骼肌和心肌等组织的功能障碍。

【药代动力学】 一次口服0.5g,健康受试者血浆最大浓度为48.5μmol/L.单一口服或静脉给予左卡尼汀0.5-2g,对健康受试者,其生物半衰期大约为2-15小时。左卡尼汀不与血浆蛋白结合。左卡尼汀的排泄途径取决于给药的途径,静脉注射12小时内从尿中回收大约70%，24小时内大约80%，口服给药,尿中回收10%。

【贮 藏】 遮光,密封保存。

Description

This medicine activates mitochondrial function by improving a carnitine deficient state, and improves symptoms such as convulsive attack and hypotonia.
It is usually used for the treatment of carnitine deficiency.

Presentation

10 packs

Feature

colorless to slightly yellow, clear solution

Active Ingredients

Levocarnitine

Effect/Efficacy

This medicine activates mitochondrial function by improving carnitine deficiency and improves symptoms such as convulsive attack and hypotonia.
It is usually used to improve carnitine deficiency.

Usage/Dosage

In general, for adults, take 15 to 30 mL (1.5 to 3 g of active ingredient) daily, in 3 divided doses. For children, take 0.25 to 1 mL (25 to 100 mg of active ingredient)/kg of body weight daily, in 3 divided doses. The dosage may be adjusted according to your symptoms. This preparation contains 5 mL (500 mg of active ingredient) in a sachet. Strictly follow the instructions.
If you miss a dose, take the dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and follow your regular dosing schedule. You should never take two doses at one time.
If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
Do not stop taking this medicine unless your doctor instructs you to do so.

Cautions

If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
If you have renal disorder.
If you are pregnant or breastfeeding.
If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Keep out of the reach of children. Store away from direct sunlight, heat and humidity.
Discard the remainder. Do not store them.

Contraindication

The most commonly reported adverse reactions include loss of appetite, diarrhea, loose stools, enlarged feeling of abdomen, facial edema, hematuria, and anemia. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
No pertinent entries.
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.