塞莫瑞林醋酸盐

通用名：sermorelin acetate

品牌名称：Geref

Sermorelin醋酸酯用于：

儿童生长激素缺乏症的诊断和治疗。 它也可能用于您的医生确定的其他条件。

Sermorelin醋酸盐是一种生长激素释放激动剂。 它通过刺激脑下垂体释放生长激素起作用。

如果出现以下情况，请勿使用sermorelin acetate：

你对任何醋酸塞莫瑞林成分过敏

如果任何这些适用于您，请立即联系您的医生或医疗保健提供者。

在使用sermorelin醋酸盐之前：

一些医疗条件可能与醋酸塞莫瑞林相互作用。如果您有任何医疗条件，请告诉您的医生或药剂师，特别是以下任何情况适用于您：

•如果您怀孕了，计划怀孕或正在哺乳

•如果您正在服用任何处方或非处方药，草药制剂或膳食补充剂

•如果您对药物，食物或其他物质过敏

•如果您有头部或脑部损伤或疾病

一些药物可能与sermorelin醋酸酯相互作用。如果您正在服用任何其他药物，请告诉您的医护人员，尤其是以下任何一种药物：

•环氧合酶抑制剂（如阿司匹林，吲哚美辛），糖皮质激素（如泼尼松），胰岛素，降低甲状腺水平的药物（如丙基硫氧嘧啶），毒蕈碱拮抗剂（如阿托品）或含生长抑素的药物或释放生长抑素的药物例如可乐定，左旋多巴），因为可以降低醋酸塞莫瑞林对诊断疾病的有效性

这可能不是可能发生的所有交互的完整列表。询问您的卫生保健提供者，如果sermorelin醋酸盐可能与您服用的其他药物相互作用。在开始，停止或更改任何药物的剂量之前，请咨询您的医疗保健提供者。

如何使用sermorelin醋酸盐：

按照你的医生指导使用sermorelin醋酸盐。检查药物上的标签是否有准确的剂量说明。

•醋酸塞莫瑞林通常在医生办公室，医院或诊所作为注射剂使用。如果您在家中使用醋酸塞莫瑞林，请仔细遵循医护人员向您提供的注射程序。

•如果醋酸塞莫瑞林含有颗粒或变色，或者如果小瓶有任何裂纹或损坏，请勿使用。

•混合时不要摇动醋酸羟丙甲纤维素。

•混合后立即使用sermorelin醋酸盐。丢弃任何未使用的药物。

•所有其他生长激素治疗应在使用醋酸塞莫瑞林前1周停止。如果您有任何疑问，请联系您的医生或药剂师。

•将本产品以及注射器和针头放在儿童接触不到的地方，远离宠物。不要重复使用针头，注射器或其他材料。使用后妥善处理。要求您的医生或药剂师解释适当处置的当地法规。

•如果您错过了一剂醋酸塞莫瑞林，请尽快使用。如果您接下来的剂量快到了，请跳过错过的剂量并返回到您的常规给药时间表。不要一次使用2剂。

询问您的健康护理提供者您可能有关于如何使用sermorelin醋酸盐的任何问题。

重要的安全信息：

•实验室测试，包括生长激素水平，可以用来监测您的进展或检查副作用。一定要保留所有医生和实验室的预约。

•怀孕和哺乳期：如果您服用醋酸塞莫瑞林时怀孕，请与您的医生讨论在怀孕期间使用醋酸塞莫司林的好处和风险。目前尚不清楚醋酸塞莫瑞林是否在母乳中排泄。如果您正在或将要在使用醋酸塞莫瑞林时进行母乳喂养，请咨询您的医生或药剂师，以讨论对宝宝的风险。

醋酸塞莫瑞林的可能副作用：

所有药物都可能引起副作用，但许多人没有副作用或轻微副作用。如果任何这些最常见的副作用持续存在或变得令人烦恼，请咨询医生：

面部潮红;头痛;恶心;注射部位疼痛，发红或肿胀;面色苍白;口中有奇怪的味道;呕吐。

如果发生任何这些严重副作用，请立即寻求医疗救助：

严重的过敏反应（皮疹，荨麻疹，瘙痒，呼吸困难，胸部紧张，口腔，脸部，嘴唇或舌头肿胀）。

这不是可能发生的所有副作用的完整列表。如果您对副作用有疑问，请联系您的医护人员。打电话给您的医生，征求有关副作用的医疗建议。您可以通过1-800-FDA-1088向FDA报告副作用。您也可以在http://www.fda.gov/medwatch报告副作用。

如果怀疑过量使用：

立即联系1-800-222-1222（美国毒物控制中心协会），当地的毒物控制中心或急诊室。症状可能包括心率和血压的变化。

正确储存sermorelin乙酸酯：

在冰箱中储存sermorelin醋酸纤维素，温度在36到46华氏度（2和8摄氏度）之间。不要冻结。远离热源，潮湿和光线存放。不要存放在浴室。将sermorelin醋酸盐放在儿童接触不到的地方，远离宠物。

一般信息：

•如果您对醋酸塞莫司林有任何疑问，请咨询您的医生，药剂师或其他医疗保健提供者。

•塞莫瑞林醋酸盐只能由患者服用。不要与其他人分享。

•如果症状没有改善或症状恶化，请咨询医生。

这个信息只是要览。它不包含有关sermorelin醋酸盐的所有信息。如果您对正在服用的药物有疑问或想了解更多信息，请咨询您的医生，药剂师或其他医疗保健提供者。

发行日期：2015年6月3日

Sermorelin acetate

Generic Name: sermorelin acetate 
Brand Name: Geref

Sermorelin acetate is used for:

Diagnosing and treating growth hormone deficiency in children. It may also be used for other conditions as determined by your doctor.

Sermorelin acetate is a growth hormone-releasing agonist. It works by stimulating the pituitary gland to release growth hormone.

Do NOT use sermorelin acetate if:

· you are allergic to any ingredient in sermorelin acetate

Contact your doctor or health care provider right away if any of these apply to you.

Before using sermorelin acetate:

Some medical conditions may interact with sermorelin acetate. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

· if you are pregnant, planning to become pregnant, or are breast-feeding

· if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

· if you have allergies to medicines, foods, or other substances

· if you have a head or brain injury or disease

Some MEDICINES MAY INTERACT with sermorelin acetate. Tell your health care provider if you are taking any other medicines, especially any of the following:

· Cyclooxygenase inhibitors (eg, aspirin, indomethacin), glucocorticoids (eg, prednisone), insulin, medicines that lower thyroid levels (eg, propylthiouracil), muscarinic antagonists (eg, atropine), or somatostatin-containing medicines or medicines that release somatostatin (eg, clonidine, levodopa) because the effectiveness of sermorelin acetate to diagnose a disorder may be decreased

This may not be a complete list of all interactions that may occur. Ask your health care provider if sermorelin acetate may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use sermorelin acetate:

Use sermorelin acetate as directed by your doctor. Check the label on the medicine for exact dosing instructions.

· Sermorelin acetate is usually administered as an injection at your doctor's office, hospital, or clinic. If you are using sermorelin acetate at home, carefully follow the injection procedures taught to you by your health care provider.

· If sermorelin acetate contains particles or is discolored, or if the vial is cracked or damaged in any way, do not use it.

· Do not shake sermorelin acetate when mixing.

· Use sermorelin acetate immediately after mixing. Discard any unused medicine.

· All other growth hormone therapy should be stopped 1 week before using sermorelin acetate. Contact your doctor or pharmacist if you have questions.

· Keep this product, as well as syringes and needles, out of the reach of children and away from pets. Do not reuse needles, syringes, or other materials. Dispose of properly after use. Ask your doctor or pharmacist to explain local regulations for proper disposal.

· If you miss a dose of sermorelin acetate, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use sermorelin acetate.

Important safety information:

· LAB TESTS, including growth hormone levels, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.

· PREGNANCY and BREAST-FEEDING: If you become pregnant while taking sermorelin acetate, discuss with your doctor the benefits and risks of using sermorelin acetate during pregnancy. It is unknown if sermorelin acetate is excreted in breast milk. If you are or will be breast-feeding while you are using sermorelin acetate, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of sermorelin acetate:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Facial flushing; headache; nausea; pain, redness, or swelling at injection site; paleness; strange taste in mouth; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch .

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include changes in heart rate and blood pressure.

Proper storage of sermorelin acetate:

Store sermorelin acetate in the refrigerator, between 36 and 46 degrees F (2 and 8 degrees C). Do not freeze. Store away from heat, moisture, and light. Do not store in the bathroom. Keep sermorelin acetate out of the reach of children and away from pets.

General information:

· If you have any questions about sermorelin acetate, please talk with your doctor, pharmacist, or other health care provider.

· Sermorelin acetate is to be used only by the patient for whom it is prescribed. Do not share it with other people.

· If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about sermorelin acetate. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: June 3, 2015