

Ostenil 交联玻璃酸钠注射液

通用中文 | 交联玻璃酸钠注射液 | 通用外文 | Hyaluronate Sodium Injection |
品牌中文 | 品牌外文 | Ostenil | |
其他名称 | 透明质酸钠预装注射液 | ||
公司 | Bio-Gen(Bio-Gen) | 产地 | 德国(Germany) |
含量 | 20mg/2ml | 包装 | 1支/盒 |
剂型给药 | 储存 | 室温 | |
适用范围 | 关节药,眼科药 |
通用中文 | 交联玻璃酸钠注射液 |
通用外文 | Hyaluronate Sodium Injection |
品牌中文 | |
品牌外文 | Ostenil |
其他名称 | 透明质酸钠预装注射液 |
公司 | Bio-Gen(Bio-Gen) |
产地 | 德国(Germany) |
含量 | 20mg/2ml |
包装 | 1支/盒 |
剂型给药 | |
储存 | 室温 |
适用范围 | 关节药,眼科药 |
【药品名称】
玻璃酸钠注射液
【英文名】
Sodium Hyaluronatc Injection
【化学名】
本品化学名称为(1→4)-O-β-D葡萄糖醛酸-(1→3)-2-乙酰氨基-2-脱氧-β-D
葡萄糖。
【主要成分】
玻璃酸钠是广泛存在于人体内的生理活性物质是一个由葡萄糖醛酸和乙酰氨基
已糖组成双糖单位聚合而成的一种粘多糖。
【性状】
本品为无色澄明的粘稠液体。
【药理、毒理】
玻璃酸钠为广泛存在于动物和人体内的生理活性物质。在人皮肤、关节滑膜液、
脐带、房水、眼玻璃体中均有分布。
本品无抗原性不引起炎症反应。
高分子量玻璃酸钠溶液的高粘弹性及仿形性使它在手术中可做为保护工具和手
术工具广泛用于各种眼科手术。术中可协助器械将组织轻柔地分离、移动和定
位。在眼前节手术中药液注入前房后前房加深便于手术操作并可保护角
膜内皮细胞及眼内组织减少术后并发症提高手术成功率。
【药代动力学】
本品为眼科手术局部辅助用药用量仅为0.2ml左右而且术后大部分仍被冲出
或抽出残余少量药液很快从房角随房水排出。
【适应症】
眼科手术辅助用药用于白内障囊内、囊外摘除术抗青光眼手术角膜移植手
术等。
【用法与用量】
本品为眼科手术辅助用药根据手术方式选择剂量眼前节手术常用量为一次
0.2ml左右。前房内注射术毕根据手术需要清除残留药液。
【不良反应】
个别患者可出现一过性眼压升高现象对症治疗即可很快恢复。
【禁忌症】
目前尚未发现。
【注意事项】
1本品使用前必须先和室温平衡。
2不要向眼内注入过量的玻璃酸钠。
3对无晶状体的糖尿症人施行后术手术时禁止使用大量玻璃酸钠。
4手术结束时可采用注洗法或抽吸法清除残留玻璃酸钠。
5本品勿于含苯扎氯铵药物接触以免产生混浊。
【规格】
0.5ml5mg
【贮藏】
遮光28℃防冻保存。
【有效期】
暂定二年。
What is sodium hyaluronate?
Sodium hyaluronate is similar to the fluid that surrounds the joints in your body. This fluid acts as a lubricant and shock absorber for the joints.
Sodium hyaluronate is used to treat knee pain caused by osteoarthritis.
Sodium hyaluronate is usually given when other arthritismedications have not been effective.
Sodium hyaluronate may also be used for purposes not listed in this medication guide.
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Important Information
You should not receive a sodium hyaluronate injection if you have an infection in your knee or in the skin around your knee.
Before taking this medicine
You should not receive sodium hyaluronate if you are allergic to it, or if you have an infection in your knee or in the skin around your knee.
To make sure sodium hyaluronate is safe for you, tell your doctor if you have ever had:
blood clots or circulation problems in your legs; oran allergy to birds, feathers, or egg products.It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
It is not known whether sodium hyaluronate passes into breast milk or if it could affect the nursing baby. Tell your doctor if you are breast-feeding.
How is sodium hyaluronate given?
Sodium hyaluronate is injected directly into your knee joint. A healthcare provider will give you this injection.
Sodium hyaluronate is usually given once every week for 3 to 5 weeks. Follow your doctor's dosing instructions very carefully.
To prevent pain and swelling, your doctor may recommend resting your knee or applying ice for a short time after your injection.
Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.
What happens if I miss a dose?
Call your doctor for instructions if you miss an appointment for your sodium hyaluronate injection.
What happens if I overdose?
Since this medication is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.
What should I avoid after receiving sodium hyaluronate?
For at least 48 hours after your injection, avoid jogging, strenuous activity, or high-impact sports such as soccer or tennis. Also avoid weight-bearing activity or standing for longer than 1 hour at a time. Ask your doctor how long to wait before you resume these activities.
Sodium hyaluronate side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
severe pain or swelling around the knee after the injection.Common side effects may include:
warmth, pain, redness, stiffness, bruising, or puffiness where the medicine was injected;nausea, stomach pain;trouble walking;back pain, joint pain, muscle pain;headache; ornumbness or tingly feeling;runny or stuffy nose, sneezing, sore throat.tired feeling; oritching or skin irritation around the knee.This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
Sodium hyaluronate dosing information
Usual Adult Dose for Osteoarthritis:
Hyalgan(R): 2 mL by intra-articular injection into
the knee once weekly for 5 weeks
Supartz(TM): 2.5 mL by intra-articular injection into the knee once weekly for
5 weeks
What other drugs will affect sodium hyaluronate?
Other drugs may interact with sodium hyaluronate, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.